TABLE 5

Contribution of PET/CT and Pathologic Responses to PFS and OS Prediction

Model	Covariate	PFS			OS
Model	Covariate	R²	P^*	HR (95% confidence interval)	R²	P^*	HR (95% confidence interval)
Bottom	Pathologic response	0.110		0.45 (0.19–1.04)	0.123		0.31 (0.10–1.02)
1		0.222	0.041		0.363	0.002
	Pathologic response			0.48 (0.20–1.14)			0.38(0.11–1.25)
	Highest SUVmax			0.42(0.18–0.98)			0.09(0.01–0.68)
2		0.251	0.021		0.172	0.180
	Pathologic response			0.37(0.15–0.89)			0.32(0.10–1.03)
	Highest TLG			0.32(0.13–0.80)			0.47(0.16–1.39)
3		0.222	0.041		0.363	0.002
	Pathologic response			0.48(0.20–1.14)			0.38(0.11–1.25)
	Total SUVmax			0.42(0.18–0.98)			0.09(0.01–0.68)
4		0.223	0.040		0.246	0.030
	Pathologic response			0.37(0.15–0.88)			0.25(0.08–0.85)
	Total TLG			0.35(0.14–0.90)			0.27(0.08–0.85)
5		0.135	0.344		0.243	0.032
	Pathologic response			0.47(0.20–1.08)			0.33(0.10–1.10)
	SUVmax by lesion			0.66(0.27–1.60)			0.17(0.02–1.33)
6		0.262	0.016		0.193	0.107
	Pathologic response			0.40(0.17–0.95)			0.33(0.10–1.07)
	TLG by lesion			0.36(0.16–0.81)			0.40(0.13–1.24)

↵* From likelihood ratio test that compares each model with 2 covariates (PET indicator plus pathologic response) with bottom model (with pathologic response alone).