TABLE 1

Patient Clinical Characteristics at Study Entry

Patient no.	Sex	Age (y)	Histologic diagnosis of LGG (WHO grade II)	Confirmation of histology	Diagnosis of LGG before baseline PET	Initial treatment of LGG before baseline PET	Initial treatment of LGG after baseline PET	Time between initial diagnosis and malignant progression (mo)	Histologic diagnosis after malignant progression	WHO grade	Confirmation of histology
1	M	56	A	Resection	Yes	Resection	Resection	106	AA	III	Resection
2	M	36	A	Resection	Yes	Resection	Resection	64	AOA	III	Resection
3	M	33	A	Biopsy	No	No	WW	44	AOA	III	Resection
4	F	40	A	Resection	Yes	Resection	Resection	53	AA	III	Resection
5	M	43	A	Biopsy	No	No	WW	4	GBM	IV	Resection
6	M	11	A	Biopsy	No	No	WW	15	AA	III	Biopsy
7	F	48	A	Biopsy	No	No	WW	5	AA	III	Resection
8	M	38	OA	Resection	No	No	Resection	15	AOA	III	Resection
9	M	85	A	Resection	No	No	Resection	10	AA	III	Resection
10	F	28	E	Resection	No	No	Resection	19	E	III	Resection
11	M	40	ODG	Biopsy	No	No	WW	11	AODG	III	Biopsy
12	M	47	A	Biopsy	No	No	WW	29	AA	III	Biopsy
13	M	50	ODG	Resection	No	No	RTx, CTx	21	GBM	IV	Resection
14	M	27	A	Biopsy	No	No	Resection	22	AA	III	Resection
15	M	64	A	Resection	No	No	Resection	16	GBM	IV	Biopsy
16	M	51	A	Resection	Yes	Resection	Resection	83	AA	III	Resection
17	F	57	A	Biopsy	No	No	WW	21	GBM	IV	Biopsy
18	M	43	A	Biopsy	Yes	WW	WW	25	AOA	III	Biopsy
19	M	40	OA	Biopsy	Yes	WW	WW	No malignant progression	OA	II	Resection
20	M	24	A	Biopsy	No	No	WW	No malignant progression	OA	II	Resection
21	M	49	OA	Biopsy	Yes	RTx	CTx	No malignant progression	OA	II	Resection
22	M	56	A	Resection	No	No	WW	No malignant progression	A	II	Resection
23	F	20	OA	Biopsy	No	No	CTx	No malignant progression	OA	II	Resection
24	F	54	A	Biopsy	No	No	WW	No malignant progression	A	II	Biopsy
25	F	43	A	Biopsy	No	No	RTx, CTx	No malignant progression	A	II	Resection
26	F	62	OA	Resection	No	No	CTx	No malignant progression	OA	II	Resection
27	M	45	A	Resection	No	No	RTx	No malignant progression	A	II	Biopsy

A = astrocytoma; AA = anaplastic astrocytoma; AOA = anaplastic oligoastrocytoma; WW = watch-and-wait strategy; GBM = glioblastoma; OA = oligoastrocytoma; E = ependymoma; ODG = oligodendroglioma; AODG = anaplastic oligodendroglioma; RTx = radiation therapy; CTx = chemotherapy.