TABLE 1

Biodistribution Data of ⁶⁴Cu-NODAGA-RM1 and ¹⁸F-AlF-NODAGA-RM1 in PC3 Tumor–Bearing Mice

Organ	⁶⁴Cu-NODAGA-RM1 (2 h after injection)	⁶⁴Cu-NODAGA-RM1 (24 h after injection)	¹⁸F-AlF-NODAGA-RM1 (2 h after injection), nonblocking	¹⁸F-AlF-NODAGA-RM1 (2 h after injection), blocking
Blood	0.17 ± 0.08	0.06 ± 0.02	0.51 ± 0.24	0.57 ± 0.11
Heart	0.22 ± 0.05	0.16 ± 0.02	0.42 ± 0.19	0.48 ± 0.09
Lungs	0.40 ± 0.21	0.27 ± 0.08	0.77 ± 0.29	2.05 ± 2.64
Liver	1.29 ± 0.56	0.75 ± 0.15	2.53 ± 0.96	1.87 ± 0.19
Spleen	0.25 ± 0.03	0.15 ± 0.02	0.39 ± 0.15	0.61 ± 0.41
Pancreas	0.41 ± 0.20	0.13 ± 0.05	5.10 ± 1.44	0.55 ± 0.13
Stomach	0.52 ± 0.25	0.28 ± 0.04	0.86 ± 0.13	1.04 ± 0.34
Brain	0.03 ± 0.01	0.02 ± 0.01	0.07 ± 0.02	0.10 ± 0.03
Intestine	0.37 ± 0.25	0.17 ± 0.09	1.68 ± 1.13	3.60 ± 1.85
Kidneys	1.39 ± 0.33	0.62 ± 0.32	4.65 ± 1.95	7.32 ± 2.09
Skin	0.29 ± 0.08	0.13 ± 0.05	0.95 ± 0.50	2.44 ± 2.48
Muscle	0.09 ± 0.04	0.03 ± 0.02	0.36 ± 0.16	0.42 ± 0.13
Bone	0.19 ± 0.05	0.07 ± 0.07	1.58 ± 0.52	1.68 ± 0.34
Tumor	4.30 ± 0.98	2.62 ± 0.32	5.25 ± 0.84	1.86 ± 0.30

Data are expressed as normalized accumulation of activity in %ID/g ± SD (n = 5).