TABLE 1

Radiotracers for Perfusion and Molecular Imaging of PVD

ModalityPerfusion/blood flowAngiogenesisAtherosclerosis
SPECT201Tl (7,21,2426)99mTc-NC100692 (47,48)
99mTc-sestamibi (27,29,31)111In-VEGF121 (45)
99mTc-pyrophosphate (76)125I-c(RGD(I)yV) (77)
99mTc-tetrofosmin
PET15O-water (32,33,36,40)76Br-nanoprobe (50)18F-FDG (5862)
C15O2 (35)68Ga-NOTA-RGD (49)18F-sodium fluoride (66)
15O2 (35,36)64Cu-DOTA-CANF-comb (52)11C-acetate (67)
13N-ammonia (34)64Cu-DOTA-VEGF121 (46)64Cu-DOTA-CANF (65)
  • CANF = C-type atrial natriuretic factor.