TABLE 2

Cox Proportional Hazards Models for Metastasis-Free Survival

		Univariate			Multivariate
Characteristic	n	RR	95% CI	P	RR	95% CI	P
MTV(2.0) (mL)
≤105	42 (50.6)		1		1
>105	41 (49.4)	3.80	1.50–9.59	0.002	3.93	1.55–9.92	0.004
TLG(45%) (g)
≤187	42 (50.6)		1		1
>187	41 (49.4)	2.47	1.056–5.79	0.037	1.98	0.66–5.93	0.222
Age (y)					Not assessed
≤15	50 (60.2)	1
>15	33 (39.8)	1.26	0.56–2.86	0.577
Sex					Not assessed
Male	62 (74.7)	1
Female	21 (25.3)	0.94	0.37–2.36	0.889
AJCC stage
IIA	34 (41.0)	1			1
IIB	49 (59.0)	2.88	1.07–7.71	0.028	1.58	0.50–4.93	0.514
Location					Not assessed
Femur	42 (50.6)	1
Tibia	28 (33.7)	1.70	0.65–4.43	0.276
Humerus	9 (10.8)	0.87	0.26–3.13	0.868
Other	4 (4.8)	0.73	0.10–5.60	0.762
Subtype					Not assessed
Osteoblastic	62 (74.7)	1
Chondroblastic	13 (15.7)	1.47	0.58–3.72	0.414
Fibroblastic	6 (7.2)	0.04	0–34.31	0.354
Other	2 (2.4)	0.05	0–1,621.33	0.565
Histologic response
Good	36 (43.4)	1			1
Poor	47 (56.6)	4.68	1.60–13.74	0.002	4.83	1.64–14.21	0.004

Data in parentheses are percentages.