TABLE 5

Modulated Genes at Positive Site Relative to Negative Site of PET+ Patients

MediaAdventitia
GeneFold changeGeneFold change
ELN0.3*EMMPRIN0.7*
TIMP20.7*VEGF0.7*
EMMPRIN0.8*TIMP20.9*
TGFβ0.8*MMP141.6*
TIMP11.8*TSP11.9*
MMP11.8*uPA2.2*
MMP121.8*COL1A15.5*
COL1A12.2*MMP139.1†
MMP133.9*MMP112.9

  • ↵* P < 0.05, Wilcoxon signed rank test.

  • ↵† MMP13 was not detected in negative sites of PET+ adventitia; median value in positive site was calculated using lowest value as 1.

  • Results are expressed as median of fold changes relative to values measured in negative site of PET+ samples.