TABLE 4

Sensitivity and Specificity of Different Methods of Volume Delineation

18F-FMISO18F-FLT
SegmentationSensitivitySpecificityAUCSensitivitySpecificityAUC
1.210.560.780.920.50.71
1.40.860.720.790.920.830.88
SUVmax
 40%100.50100.50
 50%100.50100.50
SUVmaxAorta
 1.3 ×10.560.780.960.50.73
 1.5 ×0.710.960.840.920.830.88
 1.6 ×0.1410.570.920.830.88
SUVmeanAorta
 1.3 ×10.360.6810.330.67
 1.5 ×10.40.70100.50
 1.6 ×10.560.78100.50
SUVmaxLung
 1.3 ×100.50100.50
 1.5 ×10.10.5510.330.67
 1.6 ×10.10.5510.330.67
SUVmeanLung
 1.3 ×100.50100.50
 1.5 ×100.50100.50
 1.6 ×100.50100.50
SUVmaxMuscle
 1.3 ×0.430.960.700.960.830.90
 1.5 ×0.2910.650.920.830.88
 1.6 ×0.2910.650.870.830.85
SUVmeanMuscle
 1.3 ×00.960.4810.170.59
 1.5 ×10.140.5710.170.59
 1.6 ×10.520.760.960.170.57
  • For sensitivity and specificity reference standard defined by consensus group.