Changes in 18F-EF5 Uptake After SN30000 Plus RT in Tumor Growth Delay Studies Using H460 Human NSCLC Xenografts
| Change in SUVmean (mean ± SD) | Significance (P)… | ||||
| Treatment | Average change | Percentage change | vs. baseline | vs. control group | Tumor growth delay |
| Control (n = 8) | +0.073 ± 0.067 | +16.9 ± 14.5 | <0.05 | — | — |
| SN30000 (n = 8) | +0.023 ± 0.095 | +9.2 ± 27.4 | Not significantly different | Not significantly different | Not significantly different |
| RT (n = 8) | −0.041 ± 0.059 | −7.8 ± 11.6 | Not significantly different | <0.05 | 0.006 |
| SN30000 plus RT (n = 7) | −0.082 ± 0.073 | −13.5 ± 13.5 | <0.05 | <0.01 | 0.001 |
P value is shown for changes in 18F-EF5 PET signal relative to baseline and control group and for effects of treatments on H460 tumor growth delay.