TABLE 3

Treatment Response After 3 Cycles of FOLFOX According to Percentage Changes in 18F-FLT SUVMAX

CT response after 3 cycles
Responder (n = 5)Nonresponder (n = 13)
Percentage changes in…CRPRStable diseasePDOverall response rate (%)Relative riskP
18F-FLT uptake on day 2*2.250 (95% CI, 1.084–4.671)0.029†
 ≤45.8054055.6
 >45.800810
18F-FLT reduction on day 5*2.667 (95% CI, 1.090–6.524)0.007†
 >10.6001000
 ≤10.6052162.5

  • ↵* Receiver-operating-characteristic curve analysis was used to identify optimum cutoff of percentage change in SUVMAX from baseline value for differentiating responding and nonresponding patients.

  • ↵† P value by Fisher exact test.