TABLE 4

Test–Retest Statistics for 18F-JNJ-42259152

Mean variability ± SD (%)ICC
ModelPutamenCaudate nucleusVentral striatumSubstantia nigraGlobalPutamenCaudate nucleusVentral striatumSubstantia nigraGlobal
VT
 1TCM17.4 ± 10.312.2 ± 9.612.4 ± 7.114.4 ± 10.114.1 ± 7.50.740.860.900.760.94
 2TCM14.7 ± 7.219.0 ± 19.38.9 ± 5.111.3 ± 8.514.1 ± 9.20.860.620.970.900.95
 2TCM[spec]17.3 ± 10.313.0 ± 8.912.6 ± 6.810.3 ± 6.412.7 ± 7.00.750.860.900.910.94
 2TCM[aspec]14.5 ± 6.75.4 ± 4.111.8 ± 5.512.6 ± 3.012.3 ± 5.10.860.970.950.900.95
 1TCM[intact]17.3 ± 12.813.9 ± 9.313.4 ± 5.513.6 ± 16.914.2 ± 9.60.680.830.900.570.94
BPND
 SRTM[FCx]9.4 ± 5.45.0 ± 3.24.5 ± 2.612.4 ± 11.57.8 ± 6.90.670.970.990.660.99
 MRTM[FCx]9.3 ± 5.54.6 ± 3.16.2 ± 4.311.0 ± 10.47.8 ± 6.30.680.970.980.700.99
  • Values are derived from 135-min acquisition time. Variability (%) = |VT1 − VT2|/|VT1 + VT2| × 200. n = 4 subjects.

  • SRTM[FCx] = SRTM with frontal cortex (FCx) as reference tissue; MRTM with frontal cortex (FCx) as reference tissue.