Baseline Clinical Characteristics According to Bone Marrow Status by BMB or 18F-FDG PET/CT
| BMB | 18F-FDG PET/CT | |||||
| Characteristic | BMI+ (n = 8) | BMI− (n = 125) | P | BMI+* (n = 32) | BMI−† (n = 101) | P |
| Male sex | 4 (50) | 63 (50) | 1 | 21 (66) | 46 (46) | 0.07 |
| IPI > 2 | 5 (63) | 48 (38) | 0.5 | 17 (53) | 36 (36) | 0.1 |
| Age (y) | 59 ± 11 | 57 ± 15 | 0.6 | 59 ± 10 | 57 ± 16 | 0.3 |
| Age ≥ 60 y | 4 (50) | 64 (51) | 1 | 15 (47) | 53 (52) | 0.7 |
| LDH+ | 5 (63) | 79 (63) | 1 | 23 (72) | 61 (60) | 0.3 |
| Stage III/IV | 8 (100) | 91 (73) | 0.1 | 28 (88) | 70 (70) | 0.06 |
| ECOG ≥ 2 | 2 (25) | 21 (17) | 0.6 | 7 (22) | 16 (16) | 0.4 |
| Extranodal involvement > 1 | 5 (63) | 23 (18) | 0.01 | 11 (34) | 17 (17) | 0.05 |
| BMB/BMI+ | — | — | — | 6 (19) | 2 (2) | 0.003 |
| PET/BMI+ | 6 (75) | 26 (21) | 0.003 | — | — | — |
↵* Presence of clear-cut 18F-FDG–avid bone marrow foci (unifocal of multifocal) consistent with BMI.
↵† Absence of clear-cut 18F-FDG–avid bone marrow foci (intense but homogeneous uptake is considered negative).
Qualitative data are expressed as numbers, followed by percentages in parentheses; continuous data are expressed as mean ± SD.