Biodistribution of 18F-AFETP in BALB/c Mice with Intracranial DBTs
Organ or tissue | 5 min | 30 min | 60 min |
Blood | 3.99 ± 0.38 | 1.66 ± 0.20 | 0.69 ± 0.18 |
Bone | 0.91 ± 0.17 | 1.46 ± 0.14 | 0.99 ± 0.47 |
Brain | 0.25 ± 0.03 | 0.34 ± 0.40 | 0.23 ± 0.03 |
Fat | 0.90 ± 0.08 | 0.61 ± 0.20 | 0.39 ± 0.17 |
Heart | 2.19 ± 0.19 | 2.10 ± 0.33 | 1.64 ± 0.27 |
Kidney | 65.6 ± 10.2 | 51.4 ± 6.2 | 17.8 ± 3.7 |
Large intestine | 1.81 ± 0.39 | 1.79 ± 0.24 | 1.08 ± 0.29 |
Liver | 3.19 ± 0.50 | 1.56 ± 0.15 | 0.65 ± 0.12 |
Lung | 6.06 ± 0.95 | 5.53 ± 1.87 | 2.40 ± 0.67 |
Muscle | 1.34 ± 0.19 | 1.22 ± 0.12 | 1.02 ± 0.12 |
Pancreas | 36.1 ± 5.1 | 21.9 ± 4.1 | 8.75 ± 3.0 |
Salivary glands | 5.23 ± 0.41 | 2.96 ± 0.46 | 1.28 ± 0.22 |
Small intestine | 3.97 ± 0.90 | 2.56 ± 0.38 | 1.42 ± 0.27 |
Spleen | 3.40 ± 0.42 | 2.67 ± 0.20 | 1.67 ± 0.27 |
Tumor | 4.39 ± 1.10 | 4.91 ± 1.15 | 2.46 ± 1.02 |
Data are expressed as %ID/g ± SD; n = 3 or 4 for each value.