TABLE 2

Predictive Values of ΔSUV, ΔADC, and Their Combination for Predicting Good Histologic Response

ParameterCutoff valueTrue-positiveFalse-positiveFalse-negativeTrue-negativeSensitivitySpecificityPPVNPVDiagnostic accuracy
ΔSUV≤−52%8241366.6 (34.9–90.1)86.6 (59.5–98.3)80.0 (44.4–97.5)76.5 (50.1–93.2)77.7 (57.6–91.3)
≤−31%1181791.6 (61.5–99.8)46.6 (21.3–73.4)57.9 (33.5–79.7)87.5 (47.3–99.7)66.6 (45.9–83.4)
ΔADC>13%10421183.3 (51.6–97.9)73.3 (44.9–92.2)71.4 (41.9–91.6)84.6 (54.6–98.1)77.7 (57.6–91.3)
ΔSUV + ΔADC*10221383.3 (51.6–97.9)86.7 (59.5–98.3)83.3 (51.6–97.9)86.7 (59.5–98.3)85.1 (66.1–95.7)
  • * ΔSUV + ΔADC, case was considered positive if ΔSUV ≤ −31% and ΔADC > 13%.

  • Data within parentheses are 95% CI.