Predictive Values of ΔSUV, ΔADC, and Their Combination for Predicting Good Histologic Response
Parameter | Cutoff value | True-positive | False-positive | False-negative | True-negative | Sensitivity | Specificity | PPV | NPV | Diagnostic accuracy |
ΔSUV | ≤−52% | 8 | 2 | 4 | 13 | 66.6 (34.9–90.1) | 86.6 (59.5–98.3) | 80.0 (44.4–97.5) | 76.5 (50.1–93.2) | 77.7 (57.6–91.3) |
≤−31% | 11 | 8 | 1 | 7 | 91.6 (61.5–99.8) | 46.6 (21.3–73.4) | 57.9 (33.5–79.7) | 87.5 (47.3–99.7) | 66.6 (45.9–83.4) | |
ΔADC | >13% | 10 | 4 | 2 | 11 | 83.3 (51.6–97.9) | 73.3 (44.9–92.2) | 71.4 (41.9–91.6) | 84.6 (54.6–98.1) | 77.7 (57.6–91.3) |
ΔSUV + ΔADC* | 10 | 2 | 2 | 13 | 83.3 (51.6–97.9) | 86.7 (59.5–98.3) | 83.3 (51.6–97.9) | 86.7 (59.5–98.3) | 85.1 (66.1–95.7) |
↵* ΔSUV + ΔADC, case was considered positive if ΔSUV ≤ −31% and ΔADC > 13%.
Data within parentheses are 95% CI.