TABLE 1

Demographic, Clinical, and Neuropsychologic Features of MCI Subjects

ParameteraMCImdMCInaMCIP
Demographic
 Age (y)74.5 (8.1)70.3 (9.7)73 (9.8)0.41
 Percentage female9 (81.8%)3 (42.9%)3 (33.3%)0.07
 White10 (90.9%)6 (85.7%)9 (100%)0.536
 Education (y)15.0 (3.2)16.4 (3.5)16.2 (2.8)0.608
Clinical feature
 Clinical Dementia Rating0.434
  00 (0%)0 (0%)1 (11.1%)
  0.58 (72.7%)4 (57.1%)7 (77.8%)
  13 (27.3%)3 (42.9%)1 (11.1%)
 Mini-Mental State Examination25.5 (2.8)25.9 (1.1)27.2 (2.4)0.292
 Neuropsychiatric Inventory total score2.9 (2.5)2.3 (1.5)2.4 (2.7)0.858
 Neuropsychiatric Inventory severity4.6 (4.4)3.4 (2.6)3.7 (4.9)0.755
 Memory complaint11 (100%)7 (100%)7 (77.8%)0.115
 Behavior complaint0 (0%)0 (0%)2 (22.2%)0.115
 Parkinsonism0 (0%)0 (0%)2 (22.2%)0.115
 Hallucinations0 (0%)0 (0%)0 (0%)
Neuropsychologic indices
 Logical memory8.5 (5)5.9 (2.4)11.7 (5.1)0.067
 Digit Span Forward7.7 (1.6)7.6 (2)7 (2.6)0.74
 Digit Span Backward6.2 (2.1)4.1 (0.9)5.1 (1.7)0.06
 Animals15.6 (4.3)13.7 (5)14.7 (4.4)0.647
 Trail Making Test
  Part A36.7 (13.5)44.9 (20.6)150.7 (317.7)0.429
  Part B192.5 (269.3)183.4 (106.4)373.7 (362.4)0.147
 Wechsler Adult Intelligence Scale40 (11.1)32 (11.7)33.2 (7.8)0.425
 Delayed Recall5 (4.9)4 (2.3)10.9 (5)0.018
 Boston Naming Test26.4 (2.7)22.3 (8.4)26.2 (3.5)0.625
Duration of follow-up (mo)32.5 (14.3)37.3 (14.9)40.0 (12.0)0.399
  • Data in parentheses are percentages (when followed by %) or are SDs.