TABLE 3

Dosimetry of 177Lu-ABY-027 in Mice in Comparison with 177Lu-CHX-A″-DTPA-ABD-(ZHER2:342)2 (17)

Organ177Lu-ABY-027 (Gy/MBq)177Lu-CHX-A″-DTPA-ABD-(ZHER2:342)2 (Gy/MBq)
Blood0.42 ± 0.040.51 ± 0.3
Heart0.21 ± 0.010.25 ± 0.02
Lung0.27 ± 0.020.33 ± 0.01
Liver0.28 ± 0.010.76 ± 0.03
Spleen0.32 ± 0.040.53 ± 0.4
Pancreas0.091 ± 0.0080.12 ± 0.01
Stomach0.10 ± 0.010.097 ± 0.003
Intestine0.10 ± 0.010.11 ± 0.005
Kidney0.35 ± 0.021.49 ± 0.07
Tumor1.37 ± 0.222.1 ± 0.2
Muscle0.11 ± 0.010.09 ± 0.001
Bone0.13 ± 0.020.21 ± 0.05
  • Data are presented as average Gy/MBq ± SD, n = 4.