Effect of Solvent on Enantiomeric Excess of 18F-FDOPA
| Solvent | Boiling point (°C) | Enantiomeric excess (%) |
| Dichloromethane | 39–40 | 51.0 |
| 1,2-dichloroethane | 83 | 46.5 |
| Diethyl ether | 34.6 | 97.3 |
| Diisopropyl ether | 68 | 97.5 |
| Cyclopentyl methyl ether | 106 | 97.5 |
| Methyl tert-butyl ether | 55–56 | 97.2 |
| Toluene | 111 | 97.5 |
| Xylenes | 136–140 | 97.0 |
Solvent (3 mL), catalyst 3 (3 mg), Schiff base 8 (25 mg), KOH 9N (200 μL), room temperature, 5 min.