TABLE 1

Biodistribution of 131I-FIAU in MCAO Rat Models

Biodistribution of 131I-FIAU (mean ± SD %ID/g)
After cell transplantation via:
Tissue or ratioLocal injectionVentricular injectionCarotid artery injectionTail vein injectionIn normal rats
Infarcted brain0.124 ± 0.0130.052 ± 0.0040.061 ± 0.0020.059 ± 0.0050.005 ± 0.001
Contralateral brain0.025 ± 0.0040.021 ± 0.0010.031 ± 0.0050.029 ± 0.0050.004 ± 0.001
Thyroid0.724 ± 0.0300.640 ± 0.0420.671 ± 0.0470.654 ± 0.1160.614 ± 0.065
Lung0.043 ± 0.0120.025 ± 0.0060.045 ± 0.0130.050 ± 0.0050.035 ± 0.004
Heart0.045 ± 0.0030.047 ± 0.0030.062 ± 0.0040.045 ± 0.0080.024 ± 0.011
Liver0.061 ± 0.0150.052 ± 0.0010.045 ± 0.0050.043 ± 0.0050.035 ± 0.004
Stomach0.085 ± 0.0160.073 ± 0.0100.080 ± 0.0100.062 ± 0.0090.443 ± 0.269
Pancreas0.047 ± 0.0120.045 ± 0.0070.024 ± 0.0030.050 ± 0.0170.034 ± 0.006
Spleen0.070 ± 0.0240.078 ± 0.0090.092 ± 0.0210.085 ± 0.0350.094 ± 0.011
Kidney0.083 ± 0.0440.114 ± 0.0150.121 ± 0.0140.107 ± 0.0070.112 ± 0.012
Muscle0.044 ± 0.0080.062 ± 0.0130.045 ± 0.0060.045 ± 0.0080.049 ± 0.008
Bone0.034 ± 0.0060.051 ± 0.0030.033 ± 0.0030.041 ± 0.0020.045 ± 0.011
Intestine0.110 ± 0.0200.094 ± 0.0170.114 ± 0.0190.100 ± 0.0290.113 ± 0.025
Blood0.017 ± 0.0040.012 ± 0.0050.015 ± 0.0040.029 ± 0.0310.015 ± 0.005
Ratio for infarcted brain to blood7.765 ± 3.0813.429 ± 1.3443.779 ± 1.0423.328 ± 1.6020.351 ± 0.059