TABLE 1

Characteristics of Primary Hyperparathyroid Patients

Patient no.SexAge (y)Previous thyroid surgeryPrevious hyperparathyroidism imagingPrevious hyperparathyroidism surgeryHistologyIndication for reoperation
1M47Ultrasound, 123I/99mTc-sestamibiOnceAdenomaCa-ion ≥ 1.50 mmol/L, symptoms*
2F64Ultrasound, 123I/99mTc-sestamibiTwiceNormal parathyroidCa-ion ≥ 1.50 mmol/L
3F51Total thyroidectomy for papillary thyroid cancer in 1983Ultrasound, 123I/99mTc-sestamibiOnceAdenomaCa-ion ≥ 1.40 mmol/L, symptoms*
4F57Ultrasound, 123I/99mTc-sestamibiOnceHyperplasiaCa-ion ≥ 1.40 mmol/L, symptoms*
5M31Ultrasound, 99mTc-sestamibiOnceAtypical adenomaCa-ion ≥ 1.50 mmol/L, kidney stones
6M57Ultrasound, 9mTc-sestamibiExploration twiceNothing removedCa-ion ≥ 1.40 mmol/L, osteoporosis†
7F45Ultrasound, 99mTc-sestamibiOnceNormal parathyroidCa-ion ≥ 1.40 mmol/L, 24 h urinary Ca > 15 mmol/L
8F7899mTc-sestamibiTwiceNormal parathyroid, hyperplasiaCa-ion ≥ 1.50 mmol/L
9F59Ultrasound, 123I/99mTc-sestamibiOnceHyperplasiaSymptoms*, Ca-ion ≥ 1.39 mmol/L
10F62Ultrasound, 123I/99mTc-sestamibiOnceHyperplasiaOsteoporosis†, Ca-ion ≥ 1.38 mmol/L
11F54Ultrasound, 123I/99mTc-sestamibiOnceHyperplasiaCa-ion ≥ 1.50 mmol/L
12F71Operated on for goiter in 1980sUltrasound, 123I/99mTc-sestamibiOnceAdenomaCa-ion ≥ 1.40 mmol/L, impaired kidney function
13F69Ultrasound, 123I/99mTc-sestamibiOnceHyperplasiaCa-ion ≥ 1.40 mmol/L, symptoms*
14F60Ultrasound, 123I/99mTc-sestamibiOnceAdenomaCa-ion ≥ 1.40 mmol/L, osteoporosis†
15F65Ultrasound, 123I/99mTc-sestamibiTwiceNo parathyroid tissueCa-ion ≥ 1.40 mmol/L, osteoporosis†, symptoms*
16M65Ultrasound, 123I/99mTc-sestamibiOnceNo parathyroid tissueCa-ion ≥ 1.40 mmol/L, osteoporosis†, symptoms*
17F46Ultrasound, 99mTc-sestamibiOnceNo parathyroid tissueCa-ion ≥ 1.50 mmol/L
18F65Ultrasound, 123I/99mTc-sestamibiOnceAdenomaOsteopenia†, impaired kidney function, Ca-ion ≥ 1.37 mmol/L
19F61Ultrasound, 123I/99mTc-sestamibiOnceNo parathyroid tissueOsteoporosis†, Ca- ion ≥ 1.40 mmol/L
20F57Follicular adenoma resected in 2005Ultrasound, 123I/99mTc-sestamibiOnceHyperplasia; 2 glandsOsteoporosis†, Ca- ion ≥ 1.40 mmol/L
21M56Ultrasound, 123I/99mTc-sestamibiOnceHyperplasia; 2 glandsOsteoporosis†, impaired kidney function, Ca-ion ≥ 1.30 mmol/L

  • ↵* Subjective symptoms compatible with hyperparathyroidism such as fatigue, impaired memory, depression, and gastrointestinal symptoms.

  • ↵† As defined by bone density measurements.