Patient Characteristics at Diagnosis
Characteristic | n |
Total patients* | 280 |
Sex | |
Male | 165 (59) |
Female | 115 (41) |
Age < 18 mo | 31 (11) |
Age > 18 mo | 249 (89) |
Disease site† | |
Bone only | 0 (0) |
Bone marrow only | 2 (1) |
Soft tissue only | 49 (18) |
Bone and bone marrow | 3 (1) |
Bone and soft tissue | 22 (8) |
Bone marrow and soft tissue | 29 (10) |
Bone, bone marrow, and soft tissue | 174 (62) |
Unknown | 1 |
MYCN status | |
Amplified | 85 (38) |
Nonamplified | 140 (62) |
Unknown | 55 |
Tumor histology | |
Favorable | 6 (3) |
Unfavorable | 188 (97) |
Unknown | 86 |
Ploidy | |
Hyperdiploid | 103 (47) |
Diploid | 116 (53) |
Unknown | 61 |
mIBG scans scored | |
Diagnosis | 280 |
After induction | 237 |
After ASCT | 178 |
↵* Includes only patients with mIBG-avid disease (n = 280) present at diagnosis.
↵† Indicates sites of disease at diagnosis, as determined by radiographic studies (CT/MRI, mIBG scanning), soft-tissue biopsy or bone marrow aspirate/biopsy.
Data in parentheses are percentages. Median age was 3.1 y, and age range was 0.6–29 y.