TABLE 1

Patient Characteristics at Diagnosis

Characteristicn
Total patients*280
Sex
 Male165 (59)
 Female115 (41)
Age < 18 mo31 (11)
Age > 18 mo249 (89)
Disease site
 Bone only0 (0)
 Bone marrow only2 (1)
 Soft tissue only49 (18)
 Bone and bone marrow3 (1)
 Bone and soft tissue22 (8)
 Bone marrow and soft tissue29 (10)
 Bone, bone marrow, and soft tissue174 (62)
 Unknown1
MYCN status
 Amplified85 (38)
 Nonamplified140 (62)
 Unknown55
Tumor histology
 Favorable6 (3)
 Unfavorable188 (97)
 Unknown86
Ploidy
 Hyperdiploid103 (47)
 Diploid116 (53)
 Unknown61
mIBG scans scored
 Diagnosis280
 After induction237
 After ASCT178
  • * Includes only patients with mIBG-avid disease (n = 280) present at diagnosis.

  • Indicates sites of disease at diagnosis, as determined by radiographic studies (CT/MRI, mIBG scanning), soft-tissue biopsy or bone marrow aspirate/biopsy.

  • Data in parentheses are percentages. Median age was 3.1 y, and age range was 0.6–29 y.