TABLE 4

Univariate Analysis of Factors Predictive of PFS and OS

	PFS			OS
Risk factor	Hazard ratio	95% confidence interval	P	Hazard ratio	95% confidence interval	P
Patients with interim PET/CT (n = 62)
Age (y) (>60 vs. ≤ 60)	1.448	0.566–3.706	0.440	1.030	0.354–2.994	0.957
Sex (male vs. female)	0.663	0.347–1.265	0.212	0.753	0.335–1.694	0.493
B symptoms (yes vs. no)	1.306	0.689–2.476	0.414	1.786	0.795–4.014	0.160
LDH (elevated vs. normal)	1.696	0.902–3.191	0.101	1.913	0.885–4.132	0.099
Ann Arbor stage (III–IV vs. I–II)	1.617	0.857–3.052	0.138	2.057	0.932–4.540	0.074
No. of extranodal sites (≥2 vs. 0–1)	1.784	0.943–3.373	0.075	1.863	0.860–4.036	0.115
IPI score (2–5 vs. 0–1)	1.752	0.933–3.291	0.081	1.905	0.897–4.130	0.103
PIT score (2–4 vs. 0–1)	2.387	1.125–5.063	0.023	3.649	1.557–8.556	0.003
Interim PET/CT (positive vs. negative)	5.863	2.067–16.636	<0.001	3.652	1.094–12.184	0.022
Patients with posttherapy PET/CT (n = 47)
Age (y) (>60 vs. ≤ 60)	1.766	0.609–5.117	0.295	4.943	1.535–15.912	0.007
Sex (male vs. female)	0.848	0.362–1.986	0.704	0.887	0.291–2.704	0.833
B symptoms (yes vs. no)	1.180	0.563–2.473	0.661	1.107	0.428–2.859	0.834
LDH (elevated vs. normal)	1.847	0.878–3.885	0.106	4.045	1.428–11.461	0.009
Ann Arbor stage (III–IV vs. I–II)	1.949	0.928–4.096	0.078	2.605	0.976–6.954	0.056
No. of extranodal sites (≥2 vs. 0–1)	1.086	0.413–2.856	0.866	1.520	0.348–6.626	0.578
IPI score (2–5 vs. 0–1)	1.835	0.877–3.841	0.107	2.351	0.927–5.968	0.072
PIT score (2–4 vs. 0–1)	1.583	0.546–4.594	0.398	5.127	1.535–17.119	0.008
Posttherapy PET/CT (positive vs. negative)	5.012	2.323–10.812	<0.001	3.857	1.458–10.205	0.003

LDH = lactate dehydrogenase; IPI = International Prognostic Index.