TABLE 2

Estimates of Mean Absorbed Radiation Dose in Prostate Cancer Patients and Healthy Volunteers

Target organ	¹²³I-MIP-1072 prostate cancer patients (mGy/MBq)	¹²³I-MIP-1095 prostate cancer patients (mGy/MBq)	¹²³I-MIP-1072 healthy volunteers (mGy/MBq)
Urinary bladder wall^*	0.092	0.021	0.120
Salivary glands^†	0.058	0.160	0.224
Kidneys	0.054	0.110	0.052
Distal colon	0.046	0.072	0.036
Proximal colon	0.040	0.066	0.030
Thyroid^‡	0.038	0.100	0.071
Liver	0.024	0.058	0.021
Spleen	0.023	0.047	0.015
Small intestine	0.021	0.033	0.016
Osteogenic cells	0.019	0.030	0.014
Heart wall	0.016	0.034	0.009
Lungs	0.015	0.032	0.010
Gallbladder wall	0.014	0.027	0.011
Pancreas	0.011	0.020	0.008
Adrenals	0.011	0.020	0.009
Stomach wall	0.009	0.015	0.007
Muscle	0.007	0.011	0.006
Testes	0.007	0.008	0.006
Red marrow	0.007	0.011	0.005
Thymus	0.006	0.011	0.005
Skin	0.004	0.007	0.003
Brain	0.003	0.006	0.002
Total body	0.009	0.014	0.007
Effective dose equivalent (mSv/MBq)	0.025	0.037	0.024
Effective dose (mSv/MBq)	0.022	0.032	0.021

* Assumes 4- to 8-h void.
↵† Salivary glands represented as 77-g sphere.
↵‡ Thyroid blockade in 4 of 7 prostate cancer patients and not in healthy volunteers.