Patient Characteristics
Characteristic | Number of patients |
American Joint Committee on Cancer clinical stage* | |
IIA | 11 (21.5%) |
IIB | 13 (25.5%) |
IIIA | 12 (23.5%) |
IIIB | 14 (27.5%) |
IIIC | 1 (2%) |
Tumor type | |
Invasive ductal, no special type | 45 (88%) |
Metaplastic | 3 (6%) |
Lobular | 3 (6%) |
Grade | |
1 | 4 (8%) |
2 | 28 (55%) |
3 | 17 (33%) |
Unknown | 2 (4%) |
ER status† | |
Positive | 30 (59%) |
Negative | 21 (41%) |
HER2 status‡ | |
Positive | 12 (23.5%) |
Negative | 39 (76.5%) |
Triple-negative status | |
Triple-negative | 13 (25.5%) |
Not triple-negative | 38 (74.5%) |
Surgery | |
Breast-conserving surgery | 25 (49%) |
Mastectomy | 26 (51%) |
Pathologic response | |
Responders | 27 (53%) |
Nonresponders | 24 (47%) |
↵* Version 7 (16) according to clinical examination and conventional imaging findings.
↵† Tumors were considered positive for ER (estrogen receptor) if >10% of cells showed staining by immunohistochemistry.
↵‡ Tumors were considered to be positive for HER2 if >30% of invasive tumor cells showed definite membrane staining resulting in so-called fishnet appearance.