Characteristic | Data (study population = 10) |
Age (y) | |
Median | 22.5 |
Interquartile range | 21.2–25.1 |
Body mass index (mean ± SD) (kg/m2) | 22.2 ± 1.2 |
Systolic blood pressure (mean ± SD) (mm Hg) | 117 ± 7 |
Diastolic blood pressure (mm Hg) | |
Median | 75 |
Interquartile range | 72–77 |
Fasting plasma glucose (mean ± SD) (mmol/L) | 4.6 ± 0.3 |
Presence of BAT based on 18F-FDG PET/CT (n) | 8 |
SUVmax of 18F-FDG (mean ± SD) (g/L)* | 5.8 ± 4.58 |
Presence of BAT based on 4-h 123I-MIBG SPECT/CT (n)† | 7 |
Uptake of 123I-MIBG in reference region (mean counts per voxel) after 4 h‡§ (mean ± SD) | 21.0 ± 5.6 |
Absolute uptake of 123I-MIBG in BAT after 4 h (mean maximum counts per VOI)§∥ (mean ± SD) | 37.4 ± 14.1 |
Semiquantitative uptake of 123I-MIBG (mean ± SD) after 4 h¶ | 1.8 ± 0.51 |
Presence of BAT based on 24-h 123I-MIBG SPECT/CT (n)* | 7 |
Uptake of 123I-MIBG in reference region (mean counts per voxel) after 24 h‡§ (mean ± SD) | 3.2 ± 0.5 |
Absolute uptake of 123I-MIBG in BAT after 24 h (mean maximum counts per VOI)§∥ (mean ± SD) | 9.8 ± 3.10 |
Semiquantitative uptake of 123I-MIBG (mean ± SD) after 24 h¶ | 3.1 ± 1.1 |
↵* SUVmax of 18F-FDG, defined as activity in becquerels per milliliter within region of interest divided by injected dose in becquerels per gram of body weight.
↵† Presence of BAT was determined visually.
↵‡ Uptake of 123I-MIBG in reference region (i.e., mediastinum) was calculated as mean counts per voxel in this reference region.
↵§ Decay-corrected.
↵∥ Uptake of 123I-MIBG in BAT was calculated as maximum count per voxel in VOI.
↵¶ Semiquantitative uptake of 123I-MIBG was calculated as maximum count in anatomic volumes of interest divided by mean count per voxel in reference region (i.e., mediastinum).