Demographics, Pathology, and PET Data of Study Population
| Patient no. | Age (y) | Sex | Tumor size (cm) | Histologic grade | Visual 18F-FSPG analysis* | SUVmax at 60 min | Immunohistochemistry score | ||
| 18F-FDG | 18F-FSPG | xC¯ | CD44 | ||||||
| 1 | 50 | M | 6.2 | G1 | Minor†‡ | 3.5 | 3.9‡ | 2 | 0 |
| 2 | 42 | M | 5.0 | G2 | Major§ | 10.0 | 10.4 | 1 | 2 |
| 3 | 52 | M | 6.0 | G3 | Major§ | 8.2 | 3.5 | 1 | 2 |
| 4 | 56 | M | 3.3 | G2 | Minor§ | 5.5 | 3.4 | 1 | 0 |
| 5 | 56 | M | 2.3 | NA | Minor† | 3.6 | 2.4 | NA | NA |
↵* Lesions with minor or major 18F-FSPG accumulation were regarded as positive.
↵† Isometabolic 18F-FDG uptake. Visually assessed intensity of 18F-FSPG was better than that of 18F-FDG.
↵‡ 18F-FSPG uptake of small focus that is located in central area of tumor.
↵§ Hypermetabolic 18F-FDG uptake. Intensities of 18F-FDG and 18F-FSPG uptake were same.
NA = not assessed.