Therapy study | Mouse identification | Test agent | Injection protocol | Amount of radioactivity |
α | ||||
Control group | a1, a2, a3 | PBS | Days 0 and 4 | — |
Treated group | b1, b2, b3 | 149Tb-cm09 | Days 0 and 4 | 1.1 and 1.3 MBq |
β− | ||||
Control group | c1, c2, c3, c4, c5 | PBS | Day 0 | — |
Treated group | d1, d2, d3, d4, d5 | 161Tb-cm09 | Day 0 | 11 MBq |
*Irradiation of even highly enriched 152Gd targets would presumably result in only moderate yield and quality of 149Tb because of concomitant production of side products (150Tb, 151Tb) and 149mTb.