Ex Vivo Biodistribution of 11C-Hydroxytryptophan
| Control (n = 5) | Clorgyline-pretreated (n = 6) | |
| Bone | 0.21 ± 0.07 | 0.25 ± 0.33 |
| Cerebellum | 0.38 ± 0.18 | 0.37 ± 0.14 |
| Cerebrum | 0.17 ± 0.09 | 0.17 ± 0.08 |
| Colon | 1.33 ± 0.98 | 0.79 ± 0.22 |
| Duodenum | 2.06 ± 1.32 | 2.71 ± 1.08 |
| Fat | 0.23 ± 0.12 | 0.67 ± 0.84 |
| Heart | 0.41 ± 0.25 | 0.59 ± 0.09 |
| Ileum | 1.21 ± 0.72 | 2.88 ± 2.24 |
| Kidney | 5.34 ± 1.97 | 4.38 ± 2.88 |
| Liver | 1.15 ± 0.53 | 1.87 ± 1.28 |
| Lung | 1.03 ± 0.41 | 1.29 ± 0.25 |
| Muscle | 0.46 ± 0.16 | 0.79 ± 1.07 |
| Pancreas | 2.91 ± 1.24 | 9.73 ± 2.07* |
| Plasma | 1.58 ± 0.45 | 1.14 ± 0.54 |
| Red blood cells | 0.67 ± 0.41 | 1.98 ± 1.78 |
| Spleen | 1.82 ± 0.75 | 2.91 ± 1.06 |
| Stomach | 1.69 ± 1.09 | 1.01 ± 0.59 |
↵* P < 0.01.
Uptake was measured 60 min after intravenous injection in untreated Wistar rats (control) and Wistar rats pretreated with 10 mg/kg dose of clorgyline. Uptake values are expressed as SUV ± SD.