Normal Biodistribution Studies in BALB/c Mice at 10, 30, 60, and 120 Minutes After Intravenous Injection of 18F-FPTP
| Organ | 10 min | 30 min | 60 min | 120 min |
| Blood | 0.39 ± 0.08 | 0.18 ± 0.02 | 0.04 ± 0.01 | 0.04 ± 0.02 |
| Heart | 20.57 ± 2.81 | 23.82 ± 3.23 | 21.23 ± 3.60 | 23.04 ± 3.68 |
| Lung | 4.96 ± 1.04 | 4.91 ± 1.05 | 2.96 ± 0.63 | 2.98 ± 0.27 |
| Liver | 4.81 ± 1.40 | 4.76 ± 1.06 | 3.05 ± 0.92 | 2.15 ± 0.46 |
| Spleen | 1.82 ± 0.53 | 1.79 ± 0.30 | 1.42 ± 0.44 | 1.09 ± 0.20 |
| Stomach | 4.51 ± 1.38 | 4.69 ± 1.26 | 4.34 ± 1.24 | 3.99 ± 0.91 |
| Intestine | 8.45 ± 1.92 | 11.33 ± 2.70 | 9.25 ± 5.65 | 3.69 ± 2.05 |
| Kidney | 25.65 ± 6.66 | 14.25 ± 4.36 | 11.68 ± 3.73 | 6.35 ± 2.59 |
| Pancreas | 7.33 ± 1.35 | 8.06 ± 3.73 | 7.46 ± 1.40 | 5.53 ± 1.29 |
| Normal muscle | 6.18 ± 2.22 | 6.62 ± 1.36 | 6.16 ± 1.78 | 6.06 ± 0.93 |
| Bone | 1.89 ± 0.63 | 1.79 ± 0.62 | 1.70 ± 0.71 | 1.57 ± 0.68 |
| Heart to liver | 4.46 ± 0.95 | 5.16 ± 0.98 | 7.25 ± 1.44 | 10.72 ± 2.17 |
| Heart to lung | 4.21 ± 0.47 | 4.94 ± 0.67 | 7.28 ± 1.07 | 7.72 ± 1.09 |
| Heart to muscle | 3.73 ± 1.51 | 3.69 ± 0.74 | 3.55 ± 0.48 | 3.80 ± 0.82 |
| Heart to blood | 54.10 ± 13.91 | 133.49 ± 10.45 | 523.34 ± 31.41 | 553.01 ± 23.59 |
Data are expressed as %ID/g (n = 24). Myocardial uptake of 18F-FPTP was >20 %ID/g at 10 min after radiotracer injection. Heart-to-blood ratio of 18F-FPTP was >54, and heart-to-lung and heart-to-liver ratios were >4 and >4, respectively, at 10 min.