TABLE 2

Measured VT and BPND Values of 18F-Nifene

1TCMLogan with blood sampling
Subject no.RegionVT (mL/cm3)BPND*VT (mL/cm3)BPNDMRTM, BPNDLogan ref, BPND
M1CB7.447.68
AVT20.411.7420.831.711.701.68
LG18.561.5019.111.491.451.44
FC9.040.229.310.210.200.20
SB9.260.259.500.240.240.24
M2CB6.286.13
AVT16.981.7016.431.681.671.67
LG15.291.4415.111.461.451.44
FC8.060.287.920.290.280.28
SB8.250.318.030.310.300.30
M3CB6.486.18
AVT16.931.6115.541.511.541.52
LG14.971.3113.971.261.261.27
FC8.890.378.270.340.340.34
SB9.100.408.560.390.380.38
M4CB7.427.49
AVT17.471.3517.861.381.441.35
LG15.851.1416.291.171.201.14
FC8.780.189.110.220.210.20
SB9.250.259.330.250.250.24
Average ± SDCB6.91 ± 0.616.87 ± 0.83
AVT17.95 ± 1.661.60 ± 0.1717.67 ± 2.321.57 ± 0.151.59 ± 0.121.56 ± 0.15
LG16.17 ± 1.641.35 ± 0.1616.12 ± 2.211.35 ± 0.151.34 ± 0.131.32 ± 0.15
FC8.69 ± 0.430.26 ± 0.088.65 ± 0.660.26 ± 0.060.26 ± 0.070.26 ± 0.07
SB8.96 ± 0.480.30 ± 0.078.86 ± 0.690.29 ± 0.070.29 ± 0.060.29 ± 0.07
  • * BPND for 1TCM was calculated as VT/VT(CB) − 1.

  • CB = cerebellum; AVT = anteroventral thalamus; LG = lateral geniculate body; FC = frontal cortex; SB = subiculum.