Biodistribution Results of 68Ga-DOTA-JR11 in Nude Mice Bearing HEK-hsst2 Tumor Xenografts
| Organ | 1 h | 1-h blocking* | 2 h |
| Blood | 0.6 ± 0.1 | 1.0 ± 0.2 | 0.3 ± 0.1 |
| Heart | 0.3 ± 0.1 | 0.5 ± 0.2 | 0.1 ± 0.0 |
| Liver | 0.5 ± 0.1 | 0.7 ± 0.2 | 0.3 ± 0.1 |
| Spleen | 0.5 ± 0.1 | 0.6 ± 0.2 | 0.3 ± 0.1 |
| Lung | 1.0 ± 0.2 | 1.8 ± 0.6 | 0.5 ± 0.2 |
| Kidney | 12.7 ± 3.5 | 14.0 ± 4.4 | 10.2 ± 1.6 |
| Stomach | 0.5 ± 0.1 | 0.7 ± 0.3 | 0.3 ± 0.2 |
| Intestine | 0.3 ± 0.1 | 0.6 ± 0.1 | 0.30 ± 0.2 |
| Adrenal | 2.6 ± 0.5 | 0.4 ± 0.1 | 2.4 ± 0.9 |
| Pancreas | 0.5 ± 0.1 | 0.3 ± 0.1 | 0.3 ± 0.1 |
| Muscle | 0.7 ± 0.3 | 0.2 ± 0.0 | 0.2 ± 0.1 |
| Bone | 1.4 ± 0.6 | 0.9 ± 0.2 | 1.2 ± 0.6 |
| Tumor | 23.8 ± 3.7 | 0.8 ± 0.2 | 22.4 ± 7.6 |
| Tumor–to–normal tissue ratios | |||
| Tumor to blood | 41.1 | 89.5 | |
| Tumor to liver | 50.7 | 67.8 | |
| Tumor to kidney | 1.9 | 2.2 | |
| Tumor to muscles | 33.5 | 106.6 |
↵* Coinjection with 1,500-fold excess of DOTA-JR11.
Data are %IA/g ± SD, n = 3–5.