Biodistribution Results of 68Ga-DOTATATE in Nude Mice Bearing HEK-hsst2 Tumor Xenografts
| Organ | 1 h | 1-h blocking* | 2 h |
| Blood | 0.4 ± 0.0 | 0.8 ± 0.1 | 0.3 ± 0.0 |
| Heart | 0.2 ± 0.0 | 0.3 ± 0.0 | 0.2 ± 0.0 |
| Liver | 0.4 ± 0.2 | 0.5 ± 0.1 | 0.3 ± 0.0 |
| Spleen | 0.540.2 | 0.4 ± 0.0 | 0.4 ± 0.1 |
| Lung | 2.4 ± 0.7 | 0.8 ± 0.0 | 2.4 ± 0.4 |
| Kidney | 5.2 ± 0.9 | 7.3 ± 1.6 | 4.7 ± 0.9 |
| Stomach | 8.6 ± 1.9 | 0.5 ± 0.1 | 5.5 ± 0.6 |
| Intestine | 0.8 ± 0.1 | 0.4 ± 0.2 | 1.00 ± 0.1 |
| Adrenal | 2.8 ± 0.5 | 0.6 ± 0.1 | 3.6 ± 1.0 |
| Pancreas | 10.8 ± 1.7 | 0.4 ± 0.1 | 7.2 ± 1.8 |
| Muscle | 0.4 ± 0.0 | 0.3 ± 0.1 | 0.4 ± 0.2 |
| Bone | 0.7 ± 0.3 | 0.5 ± 0.1 | 1.1 ± 0.5 |
| Tumor | 17.8 ± 2.2 | 2.2 ± 0.4 | 18.5 ± 5.8 |
| Tumor–to–normal tissue ratios | |||
| Tumor to blood | 40.4 | 66.2 | |
| Tumor to liver | 41.3 | 61.8 | |
| Tumor to kidney | 3.4 | 4.0 | |
| Tumor to muscles | 50.8 | 42.1 |
↵* Coinjection with 1,500-fold excess of DOTATATE.
Data are %IA/g ± SD, n = 3–5.