Organ | 1 h | 1-h blocking* | 2 h |
Blood | 0.5 ± 0.2 | 1.4 ± 0.2 | 0.3 ± 0.2 |
Heart | 0.3 ± 0.1 | 0.9 ± 0.4 | 0.1 ± 0.0 |
Liver | 0.6 ± 0.1 | 1.2 ± 0.1 | 0.4 ± 0.1 |
Spleen | 0.7 ± 0.4 | 1.4 ± 0.2 | 0.4 ± 0.0 |
Lung | 2.7 ± 0.7 | 3.1 ± 0.6 | 0.9 ± 0.1 |
Kidney | 10.4 ± 1.4 | 13.6 ± 0.3 | 10.5 ± 1.2 |
Stomach | 9.9 ± 2.5 | 1.6 ± 0.8 | 3.1 ± 0.4 |
Intestine | 0.7 ± 0.2 | 1.0 ± 0.5 | 0.4 ± 0.1 |
Adrenal | 1.5 ± 0.4 | Not determined | 1.6 ± 0.2 |
Pancreas | 11.4 ± 3.6 | 0.5 ± 0.0 | 3.8 ± 0.3 |
Muscle | 0.2 ± 0.0 | 0.7 ± 0.2 | 0.2 ± 0.1 |
Bone | 0.8 ± 0.1 | 1.1 ± 0.1 | 0.7 ± 0.2 |
Tumor | 30.7 ± 1.6 | 2.5 ± 0.0 | 31.6 ± 3.5 |
Tumor-to-normal tissue ratios | |||
Tumor to blood | 57.9 | 105.2 | |
Tumor to liver | 49.5 | 80.9 | |
Tumor to kidney | 3.0 | 3.0 | |
Tumor to muscles | 153.5 | 166.1 |
↵* Coinjection with 1,500-fold excess of NODAGA-JR11.
Data are %IA/g ± SD, n = 3–5.