Comparison of Multiple Uptake Parameters at Multiple Imaging Time Points in Patients with Multiple Myeloma and Precursor States
| Time point | ||||
| Parameter | 1 | 2 | 3 | 4 |
| Time (min) | 14.8 ± 4.6 | 37.2 ± 5.9 | 59.8 ± 7.9 | 121.5 ± 10.4 |
| Interval (min) | 22.40 | 22.60 | 61.70 | |
| SUV10mean | 2.50 | 2.51 | 2.51 | 2.50 |
| Mean difference (log-scale) | 0.01 | 0 | -0.01 | |
| Rate of change per minute (%)* | 0.1 | <0.1 | <0.1 | |
| P | 0.2969 | 0.759 | 0.5897 | |
| SUV10act | 3.94 | 5.09 | 5.92 | 7.32 |
| Mean difference (log-scale) | 1.37 | 0.87 | 1.37 | |
| Rate of change per minute (%)* | 9.2 | 2.9 | 2.3 | |
| P | <0.0001 | <0.0001 | <0.0001 | |
↵* Percentage change per minute values are identical for both log and original scales.
Time interval between time points 3 and 4 and 4 and 5 is approximately 3 times that of 1–2 and 2–3. Because of small number of positive malignant lesions, only mean and activity of abnormal foci with SUV > 10 (SUV10mean and SUV10act) are presented. In these patients, SUV10mean does not change significantly with time; however, SUV10act values do. Repeated baseline studies were not performed in group.