Fluorescence Distribution Observed Ex Vivo
Patient no. | Q1 | Q2 | Q3 | Q4 | Injection site | Tracer distribution throughout prostate* |
1 | 12 ± 5 | 16 ± 5 | 34 ± 8 | 37 ± 15 | L peripheral zone, R peripheral and central zone | No FL in mid gland; deposits near base and apex |
2 | 19 ± 3 | 13 ± 1 | 40 ± 9 | 28 ± 7 | Central in prostate, mostly peripheral zone | FL mostly in mid gland; hot spot L central zone |
3 | 12 ± 4 | 17 ± 8 | 36 ± 6 | 37 ± 7 | Central in prostate, peripheral zone | Evenly over all sections |
4 | 11 ± 2 | 13 ± 3 | 35 ± 13 | 41 ± 11 | Central in prostate, peripheral zone | FL mostly in central section |
5 | 13 ± 3 | 26 ± 8 | 23 ± 6 | 36 ± 4 | Central in prostate, peripheral zone | Evenly over all sections |
6 | 15 ± 4 | 35 ± 18 | 23 ± 6 | 33 ± 12 | Mostly central zone | Evenly over all sections |
7 | 16 ± 8 | 12 ± 5 | 52 ± 16 | 20 ± 4 | Mostly peripheral zone | FL in all sections; largest deposit near base |
8 | 12 ± 2 | 12 ± 5 | 44 ± 9 | 32 ± 7 | Peripheral zone | FL mostly in mid gland |
9 | 12 ± 6 | 21 ± 13 | 43 ± 19 | 27 ± 14 | L peripheral zone, R mostly central zone | FL in all sections; largest deposit near apex |
10 | 13 ± 5 | 15 ± 5 | 31 ± 4 | 41 ± 7 | Central in prostate, peripheral zone | Evenly over all sections |
11 | 10 ± 3 | 9 ± 2 | 55 ± 5 | 26 ± 4 | Peripheral zone | No FL in mid gland; deposits near base and apex |
12 | 14 ± 4 | 25 ± 12 | 24 ± 4 | 37 ± 12 | Peripheral zone and central zone | Evenly over all sections |
13 | 12 ± 4 | 13 ± 3 | 44 ± 14 | 30 ± 12 | Peripheral zone | No FL in mid gland; deposits near base (L) and apex (R) |
14 | 23 ± 11 | 19 ± 9 | 34 ± 15 | 24 ± 10 | Peripheral zone | FL in all sections; largest deposit near base |
15 | 6 ± 1 | 24 ± 11 | 32 ± 12 | 37 ± 11 | Peripheral zone and R central zone | Evenly over all sections |
16 | 28 ± 13 | 16 ± 5 | 40 ± 13 | 16 ± 5 | L central zone and peripheral zone | Evenly over all sections |
17 | 43 ± 13 | 8 ± 3 | 41 ± 12 | 8 ± 2 | L central zone | Evenly over all sections |
18 | 18 ± 8 | 10 ± 5 | 52 ± 9 | 20 ± 7 | L mostly central zone | Evenly over all sections |
19 | 7 ± 3 | 40 ± 12 | 12 ± 5 | 48 ± 11 | R mostly central zone | FL in all sections; largest deposit near base |
↵* Figure 2 shows schematic overview of signal distribution throughout prostate per patient.
FL = fluorescence.
In Q1–Q4, mean percentage of fluorescence per quadrant is shown. Injection site was determined by evaluation of fluorescence signal in different zones of prostate (central, Q1 and Q2; peripheral, Q3 and Q4). Distribution throughout prostate was determined by evaluating fluorescence in each section of prostate.