TABLE 1

Fluorescence Distribution Observed Ex Vivo

Patient no.Q1Q2Q3Q4Injection siteTracer distribution throughout prostate*
112 ± 516 ± 534 ± 837 ± 15L peripheral zone, R peripheral and central zoneNo FL in mid gland; deposits near base and apex
219 ± 313 ± 140 ± 928 ± 7Central in prostate, mostly peripheral zoneFL mostly in mid gland; hot spot L central zone
312 ± 417 ± 836 ± 637 ± 7Central in prostate, peripheral zoneEvenly over all sections
411 ± 213 ± 335 ± 1341 ± 11Central in prostate, peripheral zoneFL mostly in central section
513 ± 326 ± 823 ± 636 ± 4Central in prostate, peripheral zoneEvenly over all sections
615 ± 435 ± 1823 ± 633 ± 12Mostly central zoneEvenly over all sections
716 ± 812 ± 552 ± 1620 ± 4Mostly peripheral zoneFL in all sections; largest deposit near base
812 ± 212 ± 544 ± 932 ± 7Peripheral zoneFL mostly in mid gland
912 ± 621 ± 1343 ± 1927 ± 14L peripheral zone, R mostly central zoneFL in all sections; largest deposit near apex
1013 ± 515 ± 531 ± 441 ± 7Central in prostate, peripheral zoneEvenly over all sections
1110 ± 39 ± 255 ± 526 ± 4Peripheral zoneNo FL in mid gland; deposits near base and apex
1214 ± 425 ± 1224 ± 437 ± 12Peripheral zone and central zoneEvenly over all sections
1312 ± 413 ± 344 ± 1430 ± 12Peripheral zoneNo FL in mid gland; deposits near base (L) and apex (R)
1423 ± 1119 ± 934 ± 1524 ± 10Peripheral zoneFL in all sections; largest deposit near base
156 ± 124 ± 1132 ± 1237 ± 11Peripheral zone and R central zoneEvenly over all sections
1628 ± 1316 ± 540 ± 1316 ± 5L central zone and peripheral zoneEvenly over all sections
1743 ± 138 ± 341 ± 128 ± 2L central zoneEvenly over all sections
1818 ± 810 ± 552 ± 920 ± 7L mostly central zoneEvenly over all sections
197 ± 340 ± 1212 ± 548 ± 11R mostly central zoneFL in all sections; largest deposit near base
  • * Figure 2 shows schematic overview of signal distribution throughout prostate per patient.

  • FL = fluorescence.

  • In Q1–Q4, mean percentage of fluorescence per quadrant is shown. Injection site was determined by evaluation of fluorescence signal in different zones of prostate (central, Q1 and Q2; peripheral, Q3 and Q4). Distribution throughout prostate was determined by evaluating fluorescence in each section of prostate.