Kinetic Parameters by 2-TCM Using Parent as Input Function
| Region | K1 (mL⋅cm-3⋅min−1) | k2 (min−1) | k3 (min−1) | k4 (min−1) | K1/k2 (mL⋅cm−3) | k3/k4 | VT (mL⋅cm−3) | AIC |
| Putamen | 0.292 ± 0.053 (1.7) | 0.073 ± 0.022 (15) | 0.133 ± 0.030 (21) | 0.043 ± 0.007 (8.6) | 4.25 ± 1.07 (13) | 3.19 ± 0.97 (17) | 17.3 ± 4.6 (2.0) | −43 ± 21 |
| Caudate | 0.248 ± 0.047 (1.7) | 0.051 ± 0.022 (19) | 0.110 ± 0.063 (38) | 0.051 ± 0.014 (17) | 5.71 ± 2.69 (18) | 2.09 ± 0.93 (27) | 16.2 ± 5.5 (2.6) | −38 ± 16 |
| Midbrain | 0.203 ± 0.044 (2.6) | 0.095 ± 0.026 (13) | 0.053 ± 0.028 (34) | 0.042 ± 0.009 (22) | 2.18 ± 0.37 (11) | 1.29 ± 0.55 (18) | 4.9 ± 1.1 (3.8) | 20 ± 20 |
| Thalamus | 0.269 ± 0.042 (1.7) | 0.123 ± 0.024 (6.0) | 0.029 ± 0.018 (26) | 0.041 ± 0.023 (23) | 2.26 ± 0.55 (4.7) | 0.71 ± 0.20 (12) | 3.8 ± 0.8 (3.8) | 10 ± 16 |
| Cerebellum | 0.265 ± 0.031 (1.2) | 0.141 ± 0.025 (3.5) | 0.013 ± 0.005 (23) | 0.023 ± 0.013 (30) | 1.94 ± 0.44 (2.6) | 0.67 ± 0.32 (15) | 3.2 ± 0.7 (6.3) | −4 ± 29 |
Values are mean ± SD (n = 10), with percentage SE (which is inversely related to identifiability of parameters) in parentheses.