Efficacy of 99mTc-3PRGD2 Imaging for Diagnosis of Primary Lung Cancer
| Analysis | Time (h) | Mode | Criteria for positivity | Sensitivity (%) | Specificity (%) | Accuracy (%) | Positive predictive value (%) | Negative predictive value (%) |
| Semiquantitative | 1 | Planar | T/B > 1.2 | 88 | 67 | 84 | 93 | 53 |
| SPECT | T/B > 1.5 | 88 | 58 | 83 | 91 | 50 | ||
| 4 | Planar | T/B > 1.4 | 72 | 60 | 70 | 91 | 26 | |
| SPECT | T/B > 1.9 | 72 | 62 | 70 | 89 | 33 | ||
| Visual | 1 | Planar | * | 93 | 58 | 87 | 92 | 64 |
| SPECT | * | 97 | 58 | 90 | 92 | 78 | ||
| 4 | Planar | * | 98 | 67 | 93 | 93 | 89 | |
| SPECT | * | 98 | 67 | 93 | 93 | 89 |
↵* Higher than soft tissue, but also considered volume effect, necrosis, and metastasis.
Data are for analysis of lung lesions in 70 patients (malignant, 58; benign, 12).