Radiation Dosimetry Estimates per Unit Administered Activity for 18F-RGD-K5 for Human Adult Male Phantom in 1- and 4.8-Hour Bladder-Voiding Models, Based on Primate Biodistribution Data
| Organ | 1-h void model (μGy/MBq) | 4.8-h void model (μGy/MBq) |
| Urinary bladder wall | 110 ± 65 | 400 ± 100 |
| Upper large intestine wall | 74 ± 8.3 | 77 ± 8.5 |
| Small intestine | 66 ± 6.8 | 69 ± 6.9 |
| Testes | 44 ± 2.3 | 49 ± 2.0 |
| Kidneys | 38 ± 6.2 | 39 ± 6.2 |
| Uterus | 19 ± 0.3 | 37 ± 4.6 |
| Lower large intestine wall | 29 ± 2.0 | 38 ± 2.3 |
| Ovaries | 18 ± 1.2 | 26 ± 1.2 |
| Liver | 14 ± 2.5 | 15 ± 2.4 |
| Gallbladder wall | 13 ± 1.8 | 14 ± 1.7 |
| Spleen | 11 ± 4.2 | 11 ± 4.0 |
| Heart wall | 11 ± 2.6 | 11 ± 2.5 |
| Osteogenic cells | 8.2 ± 1.7 | 9.0 ± 1.4 |
| Stomach wall | 8.6 ± 1.4 | 9.0 ± 1.4 |
| Pancreas | 8.6 ± 1.6 | 8.9 ± 1.6 |
| Muscle | 6.7 ± 1.0 | 8.8 ± 0.4 |
| Red marrow | 7.1 ± 1.0 | 8.5 ± 0.7 |
| Adrenals | 7.9 ± 1.5 | 8.1 ± 1.5 |
| Lungs | 5.3 ± 1.2 | 5.3 ± 1.2 |
| Thymus | 5.3 ± 1.2 | 5.3 ± 1.2 |
| Skin | 4.3 ± 0.8 | 5.1 ± 0.7 |
| Thyroid | 4.6 ± 1.1 | 4.6 ± 1.2 |
| Breast | 4.2 ± 1.0 | 4.2 ± 1.0 |
| Brain | 1.9 ± 0.6 | 1.9 ± 0.6 |
| Total body | 7.8 ± 1.1 | 9.7 ± 0.6 |
| Effective dose (μSv/MBq) | 23 ± 0.3 | 40 ± 4.4 |
Data are mean ± SD; n = 3.