TABLE 4

Results of Univariate and Multivariate Analyses in All Patients (n = 468)

	Univariate analysis				Multivariate Cox-hazard model analysis
Parameter	χ²	Hazard ratio	95% Cl	P	χ²	Hazard ratio	95% Cl	P
Age	1.74	1.026	0.956–1.096	0.1476
Sex	0.53	0.837	0.505–1.333	0.4647
NYHA functional class	35.2	2.121	1.669–2.730	<0.001	7.75	1.423	1.121–1.827	0.0054
Systolic blood pressure	0.32	0.988	0.503–1.430	0.6154
Diastolic blood pressure	0.45	0.972	0.517–1.381	0.5401
Heart rate	0.88	0.993	0.979–1.006	0.3473
Diabetes mellitus	3.24	1.536	0.962–2.388	0.0716
Hypertension	0.005	0.982	0.603–1.547	0.9416
Dyslipidemia	17.2	0.263	0.172–0.529	<0.001	5.67	0.397	0.163–0.851	0.0172
Atrial fibrillation	0.55	0.827	0.484–1.345	0.4566
Ventricular tachycardia/ventricular fibrillation	0.37	1.143	0.738–1.744	0.5412
lschemic heart disease	2.86	1.475	0.940–2.279	0.1133
History of myocardial infarction	0.002	0.976	0.563–1.569	0.9871
Washout ratio	22.8	1.054	1.031–1.078	<0.001	2.21	1.020	0.993–1.047	0.137
Early HMR	17.0	0.311	0.163–0.562	<0.001	0.37	0.725	0.256–1.928	0.5428
Late HMR	40.0	0.127	0.062–0.251	<0.001	6.18	0.215	0.064–0.718	0.0129
Diuretics	12.1	2.723	1.521–5.189	0.001	1.53	1.482	0.795–2.929	0.2164
Angiotensin-converting enzyme inhibitors	0.11	0.906	0.501–1.582	0.7662
Angiotensin-receptor blockers	0.001	0.998	0.625–1.557	0.996
Calcium channel blockers	0.25	1.142	0.660–1.873	0.6196
β-blockers	0.35	0.845	0.455–1.514	0.5845
Nitrates	19.9	3.182	1.935–5.246	<0.001	3.98	1.699	1.016–2.813	0.0461
Nicorangil	0.14	0.870	0.386–1.696	0.7044
Antiarrhythmic drugs	1.29	0.783	0.510–1.192	0.256
Antiplatelet agent	0.07	0.942	0.615–1.468	0.7884
Anticoagulation agent	2.48	1.414	0.918–2.171	0.155
Statins	9.35	0.391	0.198–0.732	0.002	3.26	0.526	0.225–1.057	0.071
BNP concentration (n = 267)	14.1	1.000	1.000–1.001	0.0002
Hemoglobin level	92.5	0.702	0.649–0.810	<0.001	7.48	0.821	0.708–0.946	0.0062
Estimated GFR	16.1	0.977	0.963–0.985	<0.001	5.08	0.984	0.970–0.998	0.0243
Left ventricular ejection fraction	0.28	0.960	0.509–1.481	0.6532
End-diastolic left ventricular diameter	2.07	1.016	0.994–1.038	0.1403
End-systolic left ventricular diameter	0.93	1.012	0.987–1.038	0.3344
End-diastolic interventricular septal wall thickness	0.46	0.971	0.891–1.052	0.4963
End-diastolic posterior wall thickness	0.17	0.979	0.884–1.077	0.6801
Left atrial diameter	0.59	1.050	0.827–1.355	0.3813