TABLE 1

Distribution Volume of 18F-FEAnGA in Different Regions of Brain in Control Rats (n = 4) and Rats Infected with HSV-1 (n = 8)

Region of brainHSV-1 (n = 8)Control (n = 4)
Whole brain0.12 ± 0.03*0.08 ± 0.01
Striatum0.09 ± 0.03*0.04 ± 0.02
Frontal cortex0.17 ± 0.02*0.13 ± 0.03
Hippocampus0.10 ± 0.02*0.05 ± 0.03
Parietal/temporal/occipital cortex0.13 ± 0.03†0.09 ± 0.01
Bulbus olfactorius0.17 ± 0.02*0.14 ± 0.02
Cerebellum0.12 ± 0.030.07 ± 0.02
Frontopolar cortex0.20 ± 0.020.17 ± 0.04
Brainstem0.11 ± 0.03*0.06 ± 0.02
Thalamus0.08 ± 0.03*0.03 ± 0.01
Midbrain0.10 ± 0.02*0.05 ± 0.03

  • ↵* P < 0.05 compared with controls.

  • ↵† This brain region was excluded from statistical analysis.

  • Data are mean ± SD mL/mg.