TABLE 2

11C-DPA-713 Residence Times in Measured Tissues (Hours)

Tissue or regionMen (n = 3)Women (n = 3)Mean ± SD (n = 6)
Adrenals3.55E–043.57E–043.56E–04 ± 1.50E–04
Brain1.27E–021.09E–021.18E–02 ± 3.77E–03
Breasts1.09E–031.09E–03 ± 7.15E–04
Gallbladder contents1.73E–049.97E–051.36E–04 ± 1.24E–04
Lower large intestine wall8.63E–041.58E–031.22E–03 ± 7.45E–04
Small intestine8.64E–031.26E–021.06E–02 ± 3.72E–03
Stomach3.92E–032.10E–033.01E–03 ± 1.25E–03
Upper large intestine wall1.89E–034.13E–033.01E–03 ± 3.56E–03
Heart contents3.71E–033.55E–033.63E–03 ± 2.17E–03
Heart wall6.68E–036.10E–036.39E–03 ± 3.64E–03
Kidneys1.15E–021.01E–021.08E–02 ± 3.11E–03
Liver4.69E–023.50E–024.10E–02 ± 1.04E–02
Lungs6.87E–026.36E–026.62E–02 ± 2.20E–02
Ovaries8.90E–058.90E–05 ± 5.80E–05*
Pancreas3.43E–032.72E–033.08E–03 ± 1.41E–03
Red marrow1.14E–021.94E–021.54E–02 ± 9.16E–03
Spleen7.99E–036.17E–037.08E–03 ± 2.19E–03
Testes1.83E–041.83E–04 ± 2.52E–05
Thyroid4.17E–043.40E–043.79E–04 ± 1.52E–04
Urinary bladder contents2.19E–041.26E–041.72E–04 ± 1.21E–04
Uterus or uterine wall7.33E–047.33E–04 ± 1.75E–04
Remainder of body0.2980.3070.303 ± 0.050
  • * Ovaries were not identified positively in 1 female subject (F2); thus, mean ovarian residence time is based on measurements from 2 subjects. Mean values for sex-specific regions, including breasts, uterus or uterine wall, and testes, are based on measurements from 3 subjects of each sex.