TABLE 2

Half Maximal Inhibition Concentration of NA Prodrugs

Cell lineGemcitabine (μM)Clofarabine (μM)
WT0.00730 ± 0.005970.386 ± 0.202
WT+CDA0.109 ± 0.08800.0894 ± 0.0516
10K38.5 ± 28.6112 ± 68.1
  • Values are presented as mean ± SD. Results are representative of 3 independent experiments at 72 h of drug incubation.