TABLE 2

Univariate Analyses of SUVs and Survival

			OS		DFS		LRC inside field		LRC inside + outside field		Distant metastasis-free survival
Variable	Median	Interquartile range	Hazard ratio	P	Hazard ratio	P	Hazard ratio	P	Hazard ratio	P	Hazard ratio	P
Primary tumor
SUV_max at diagnosis	14	10.6–16.9	1.03	0.368	0.99	0.769	1.01	0.837	1.01	0.838	0.93	0.191
SUV_max after RT	3.7	2.7–5.5	1.27	<0.0001	1.16	0.004	1.19	0.002	1.17	0.002	1.16	0.066
Reduction (%) in SUV_max	70	44–80	0.53	0.158	0.62	0.229	0.52	0.159	0.60	0.257	0.52	0.242
Regional LN^*
SUV_max at diagnosis	11	6.4–15.4	0.99	0.826	1.01	0.842	1.02	0.582	1.01	0.692	0.94	0.266
SUV_max after RT	3.1	2.4–4.1	1.32	0.004	1.32	0.001	1.26	0.011	1.29	0.002	1.11	0.533
Reduction in SUV_max	64	32–80	0.19	0.070	0.48	0.330	0.65	0.681	0.55	0.481	0.26	0.213
SUV_max sum
All LNs at diagnosis	17.2	10.4–30.6	0.98	0.365	0.99	0.903	0.98	0.632	1.01	0.468	0.98	0.374
All LNs after RT	6.3	3.3–9.5	1.01	0.776	1.09	0.065	1.05	0.374	1.29	0.007	0.99	0.950
Reduction (%) in all LNs	60	43–80	0.20	0.098	0.45	0.321	0.41	0.408	0.55	0.332	0.32	0.337
Target lesion^† SUV_max
At diagnosis	15.4	11.1–17.9	1.04	0.264	1.01	0.802	1.00	0.982	0.99	0.938	0.97	0.645
After RT	3.8	2.7–5.2	1.27	<0.0001	1.17	0.003	1.19	0.004	1.17	0.004	1.17	0.044
Reduction (%)	72	55–80	0.06	0.002	0.03	0.001	0.06	0.007	0.04	0.002	0.07	0.028
Sum of primary tumor + LNs SUV_max
At diagnosis	24.4	15.1–38.3	0.98	0.422	1.00	0.678	0.99	0.524	1.01	0.622	0.99	0.745
After RT	7.9	5.9–13.9	1.06	0.083	1.13	0.001	1.06	0.091	1.13	0.001	1.08	0.115
Reduction (%)	65	45–74	0.04	0.004	0.06	0.033	0.06	0.020	0.07	0.021	0.11	0.163