TABLE 1

In Vivo Biodistribution of 18F-(2S,4R)4-Fluoroglutamine in Male ICR Mice After Intravenous Injection

Organ2 min30 min60 min120 min240 min
Blood6.19 ± 0.832.72 ± 0.172.05 ± 0.160.83 ± 0.120.48 ± 0.06
Heart4.31 ± 0.323.16 ± 0.252.86 ± 0.471.86 ± 0.241.24 ± 0.19
Muscle1.62 ± 0.102.48 ± 0.162.86 ± 0.341.81 ± 0.260.94 ± 0.15
Lung7.15 ± 0.765.36 ± 0.494.37 ± 0.281.69 ± 0.101.03 ± 0.15
Kidney16.1 ± 1.039.93 ± 0.527.60 ± 0.842.15 ± 0.341.25 ± 0.21
Pancreas17.2 ± 1.0019.7 ± 2.1617.5 ± 2.289.57 ± 1.225.92 ± 0.87
Spleen7.51 ± 0.445.39 ± 0.724.22 ± 0.382.02 ± 0.161.15 ± 0.14
Liver6.92 ± 0.926.23 ± 0.505.70 ± 0.622.46 ± 0.261.30 ± 0.18
Skin2.72 ± 0.054.01 ± 0.242.94 ± 0.682.17 ± 0.161.25 ± 0.13
Brain0.54 ± 0.050.51 ± 0.050.53 ± 0.070.57 ± 0.050.45 ± 0.06
Bone3.93 ± 0.375.64 ± 0.697.93 ± 1.0214.4 ± 1.3119.4 ± 0.50
  • Data represented as %ID/g, mean ± SD (5 mice per time point).