Questions Asked by QUADAS Tool to Assess Quality of Studies Evaluating Diagnostic Tests
Question no. | QUADAS tool question |
1 | Was the spectrum of patients representative of the patients who will receive the test in practice? |
2 | Were selection criteria clearly described? |
3 | Is the reference standard likely to correctly classify the target condition? |
4 | Is the time period between reference standard and index test short enough to be reasonably sure that the target condition did not change between the 2 tests? |
5 | Did the whole sample or a random selection of the sample receive verification using a reference standard of diagnosis? |
6 | Did patients receive the same reference standard regardless of the index test result? |
7 | Was the reference standard independent of the index test (i.e., the index test did not form part of the reference standard)? |
8 | Was the execution of the index test described in sufficient detail to permit replication of the test? |
9 | Was the execution of the reference standard described in sufficient detail to permit its replication? |
10 | Were the index test results interpreted without knowledge of the results of the reference standard? |
11 | Were the reference standard results interpreted without knowledge of the results of the index test? |
12 | Were the same clinical data available when test results were interpreted as would be available when the test is used in practice? |
13 | Were uninterpretable/intermediate test results reported? |
14 | Were withdrawals from the study explained? |