TABLE 1

Subject Characteristics and Hepatic Galactose Kinetics

Subject no.	Sex	Age (y)	Body weight (kg)	Hepatic blood flow (L blood/min)	V_max (mmol/min)	K_m (mmol/L blood)	V_max/K_m (L blood/min)	V_max/(FK_m)	Approximation of K_syst to F
1	Male	65	86	1.17 ± 0.06	1.81 ± 0.26	0.59 ± 0.15	3.05 ± 0.22	2.60 ± 0.19	93%
2	Male	63	90	0.93 ± 0.08	5.34 ± 0.68	2.17 ± 0.36	2.46 ± 0.07	2.65 ± 0.07	93%
3	Male	55	92	1.76 ± 0.14	4.21 ± 0.33	1.00 ± 0.15	4.23 ± 0.18	2.41 ± 0.10	91%
4	Female	70	45	0.70 ± 0.04	2.33 ± 0.41	1.08 ± 0.37	2.16 ± 0.29	3.07 ± 0.41	95%
5	Male	58	73	1.34 ± 0.12	4.77 ± 0.56	1.52 ± 0.28	3.13 ± 0.13	2.34 ± 0.09	90%
6	Female	61	76	0.94 ± 0.07	1.95 ± 0.35	0.84 ± 0.25	2.31 ± 0.21	2.45 ± 0.23	91%
7	Male	55	92	0.90 ± 0.05	2.16 ± 0.39	0.87 ± 0.33	2.47 ± 0.36	2.76 ± 0.40	94%
8	Male	61	74	1.10 ± 0.10	2.26 ± 0.36	0.82 ± 0.30	2.77 ± 0.42	2.52 ± 0.38	92%
Mean ± SE				0.94 ± 0.02	2.66 ± 0.13	0.95 ± 0.08	2.74 ± 0.05	2.53 ± 0.10	92%

V_max/K_m = intrinsic clearance of galactose; F = hepatic blood flow; K_syst = hepatic systemic clearance of galactose (L blood/min); mean ± SE = weighted mean ± SE of weighted mean.
Individual values are given as estimate ± SE of estimate.