TABLE 2

Main Results of Clinical Study

ParameterStudy group (n = 115)Control group (n = 230)P
Mean age (y)59581.0
Matching criteria
 Microorganism SAB73 (64%)146 (64%)1.0
 SSB30 (26%)60 (26%)1.0
 Enterococcus12 (10%)24 (10%)1.0
 Community acquisition70%68%0.71
Treatment delay > 48 h27%45%0.01
Fever > 72 h46%37%0.13
Portal of entry unknown52%46%0.30
Central venous catheter not removed > 48 h5%8%0.50
Blood cultures > 72 h*16%6%<0.01
Immunosuppression22%17%0.30
Known malignancy14%17%0.53
Echocardiography performed83%29%<0.01
Metastatic foci (no. of patients)68%36%<0.01
Endocarditis18%8%0.01
Relapse of infection2.6%7.4%0.09
Overall mortality19%32%<0.01
Median treatment days
 Metastatic infection present4536<0.01
 Metastatic infection absent14140.38
 Length of hospital stay
 Metastatic infection present27280.51
 Metastatic infection absent14140.61
  • * Not routinely obtained in control group.