Main Metabolites Detected by MRS, Their Chemical Shift Position, and Interpretation
Metabolite | Peak position (ppm) | Echo time used | Interpretation | Found in normal tissue? |
Choline | 3.2 | Short and long | Membrane turnover | Yes |
Creatine/phosphocreatine | 3.02, 3.8 | Short and long | Energy metabolism | Yes |
NAA | 2.01, 2.6 | Short and long | Neural tissue integrity | Yes |
Lipids | 0–2 | Short and long | Tissue necrosis | Only as contamination |
Lactate | 1.33 | Short and long | Anaerobic glycolysis | No |
Taurine | 3.36 | Short | Pediatric tumors | Below sensitivity |
Myoinositol | 3.56, 4.06 | Short | Glial activation | Yes |
Clinically used echo times are 20–30 ms (short), 135–144 ms (long), or 270 ms.