TABLE 2.

Patient and Tumor Characteristics and Outcomes (n = 21), Including Individual Patient Data on All Parameters Collected

During-treatment SUVmaxSUVmax change from baseline (%)CT
Patient no.SexAge (y)Tumor stageSmoking historyNo. of prior treatment regimensHistologyBaseline SUVmax1–2 wk6 wk1–2 wk6 wk6 wkBest responseTime to progression (mo)OS (mo)
1F69IVNone1Adenocarcinoma1.813.153.6474101Stable diseaseStable disease1.94.5
2M73IVFormer1Adenocarcinoma3.243.172.76−2−15Stable diseasePR3.67.5
3M79IVFormer1Adenocarcinoma5.935.574.12−6−31PRPR9.014.1
4F65IVFormer2SCC1.751.981.2813−27Stable diseaseStable disease1.63.6
5F50IVNone2Adenocarcinoma4.70NDNDNANAPRPR5.111.4
6F54IVNone2Adenocarcinoma1.982.243.701387PDPD1.24.7
7M62IVFormer2SCC5.535.164.97−7−10PRPR7.911.6
8M75IVFormer1Adenocarcinoma1.261.09ND−13NAPDPD0.40.9
9F62IVNone2Adenocarcinoma2.92NDNDNANAStable diseaseStable disease3.38.1
10F45IVNone2SCC2.372.983.132633Stable diseaseStable disease2.212.3
11F46IVNone3Adenocarcinoma4.613.573.41−23−26PDPD1.64.2
12F73IVNone1SCC2.60NDNDNANAStable diseaseStable disease2.86.5
13M59IVFormer2SCC1.981.021.21−48−39PDPD1.02.6
14F39IVNone2Adenocarcinoma3.322.961.86−11−44Stable diseasePR3.98.5
15F64IVNone2Adenocarcinoma4.763.312.45−30−49PRPR5.511.8+
16M47IIIBFormer2SCC3.601.902.03−47−44PRPR4.48.8
17F72IVNone1Adenocarcinoma2.332.463.47649Stable diseaseStable disease2.44.9
18M61IVFormer2Adenocarcinoma4.954.623.49−7−29PRPR6.712.1+
19F63IVFormer2Adenocarcinoma1.631.79ND10NAPDPD0.81.4
20M55IVCurrent2Adenocarcinoma2.542.493.24−228Stable diseaseStable disease2.56.7
21F52IVNone2Adenocarcinoma3.582.962.79−17−22Stable diseasePR4.212.4+
  • SCC = squamous cell carcinoma; PD = progressive disease; PR = partial response; ND = not done; NA = not applicable; + = patients alive at last follow-up.