Change in MBF and Coronary Vascular Resistance over Time in Patients with Baseline and Follow-up Scanning
| Patients with features of metabolic syndrome | |||||
| Variable | All patients | No features | 1 or 2 features | 3 or more features | P |
| Rest MBF (mL/min/g) | |||||
| Baseline | 0.83 ± 0.24 | 0.70 ± 0.16 | 0.82 ± 0.26 | 0.87 ± 0.24 | 0.07 |
| Follow-up | 0.79 ± 0.26 | 0.74 ± 0.20 | 0.79 ± 0.2 | 0.81 ± 0.27 | 0.23 |
| Change at 1 y | −0.04 ± 0.07 | 0.03 ± 0.26 | −0.02 ± 0.25 | −0.06 ± 0.28 | 0.84 |
| Hyperemic MBF (mL/min/g of tissue) | |||||
| Baseline | 1.69 ± 0.57 | 1.80 ± 0.58 | 1.66 ± 0.51 | 1.72 ± 0.65 | 0.19 |
| Follow-up | 1.78 ± 0.68 | 1.71 ± 0.57 | 1.78 ± 0.69 | 1.79 ± 0.69 | 0.95 |
| Change at 1 y | 0.08 ± 0.68 | −0.09 ± 0.82 | 0.12 ± 0.66 | 0.07 ± 0.69 | 0.82 |
| Coronary vasodilator reserve | |||||
| Baseline | 2.13 ± 0.75 | 2.60 ± 0.84 | 2.11 ± 0.66 | 2.09 ± 0.84 | 0.01 |
| Follow-up | 2.37 ± 0.98 | 2.34 ± 0.70 | 2.35 ± 1.00 | 2.40 ± 1.01 | 0.91 |
| Change at 1 y | 0.24 ± 1.00 | −0.26 ± 1.06 | 0.24 ± 1.00 | 0.32 ± 0.98 | 0.96 |
| Rest coronary vascular resistance (mL/min/g/mm Hg) | |||||
| Baseline | 120.1 ± 33.2 | 121.5 ± 24.7 | 121.3 ± 34.3 | 118.3 ± 33.3 | 0.07 |
| Follow-up | 125.9 ± 40.2 | 124.8 ± 37.5 | 123.4 ± 38.6 | 129.4 ± 42.8 | 0.33 |
| Change at 1 y | 5.75 ± 40.9 | 3.38 ± 47.7 | 2.12 ± 39.4 | 11.1 ± 41.6 | 0.46 |
| Hyperemic coronary vascular resistance (mL/min/g/mm Hg) | |||||
| Baseline | 59.3 ± 24.3 | 51.2 ± 16.8 | 58.7 ± 20.7 | 61.5 ± 29.4 | 0.34 |
| Follow-up | 58.4 ± 25.6 | 56.4 ± 20.6 | 57.5 ± 26.1 | 59.9 ± 26.0 | 0.99 |
| Change at 1 y | −0.93 ± 27.1 | 5.29 ± 28.8 | −1.26 ± 24.5 | −1.56 ± 30.2 | 0.89 |
n = 234 for all patients, 16 for patients with no features of metabolic syndrome, 125 for patients with 1 or 2 features, and 93 for patients with 3 or more features. Data are mean ± SD.