Study Population
| Characteristic | Data |
| PE patients | |
| Sex | 29 men and 7 women |
| Age | 62.8 ± 8.6 y (range, 49–83 y) |
| Smoking history | 27 ± 13 pack-years (range, 10–91 pack-years) |
| %FEV1 | 75.4% ± 12.4% (range, 42.7%–95.7%) |
| FEV1 | 2,328 ± 287 cm3 (range, 1,284–3,685 cm3) |
| %VC | 87.6% ± 11.7% (range, 81.7%–115.4%) |
| A-aDO2 | 14.6 ± 9.7 torr (range, 2–36 torr) |
| Low-attenuation areas* | 15.4% ± 7.9% (range, 4.3%–34%) |
| Perfusion defects† | 20.8% ± 7.4% (range, 8.9%–37%) |
| Controls | |
| Sex | 9 men and 7 women |
| Age | 54 ± 3.1 y (range, 51–62 y) |
| %FEV1 | 99.4% ± 2.9% (range, 97.4%−111.7%) |
| FEV1 | 3,417 ± 208 cm3 (range, 2,951–3,882 cm3) |
| %VC | 95.4% ± 5.7% (range, 95.8%−109.5%) |
* Percentage of total-lung voxels with attenuation < −960 HU on CT.
† Percentage of total-lung voxels with radioactivity < 10% of maximum on perfusion SPECT.
%FEV1 = predicted forced expiratory volume in 1 s; FEV1 = forced expiratory volume in 1 s; %VC = predicted vital capacity.