TABLE 5

Radiation Dose Due to Resting Dose of Radiopharmaceuticals Used for MPI, Compared with That of BMS747158

82Rb*
Parameter201Tl*99mTc-sestamibi*2-Dimensional bismuth germanate3-Dimensional bismuth germanateBMS747158
Rest dose (MBq)1113701,850555111
Critical organOvariesGallbladderKidneysKidneysKidneys
Critical organ dose per rest study (mSv)811410.83.27.3
ED per rest study (mSv)243.32.30.702.1
  • * Middle of American Society of Nuclear Cardiology guideline range was used for rest dose. Administered dose ranges for 201Tl- and 99mTc-sestamibi are from Hansen et al. (21). Administered dose ranges for 82Rb are from Machac et al. (22). Radiation dose for 201Tl- and 99mTc-sestamibi is from ICRP 80 (20). Radiation dose from 82Rb is from Senthamizhchelvan et al. (23).